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Chicken Alfredo Casserole Recipe

5 Stars 4 Stars 3 Stars 2 Stars 1 Star 4.2 from 20 reviews
  • Author: Claire
  • Prep Time: 15 minutes
  • Cook Time: 30 minutes
  • Total Time: 45 minutes
  • Yield: 6 servings
  • Category: Main Course
  • Method: Baking
  • Cuisine: Italian-American

Description

This comforting Chicken Alfredo Casserole is a creamy, cheesy baked pasta dish featuring tender chicken, savory onions and garlic, penne pasta, and rich Alfredo sauce. Topped with a golden blend of mozzarella and cheddar cheeses, it’s an easy weeknight meal that serves six and takes just 45 minutes from start to finish.


Ingredients

Scale

Chicken and Vegetables

  • 3 boneless, skinless chicken breasts, cut into bite-sized pieces
  • 1 small red onion, chopped
  • 3 cloves garlic, minced

Pasta and Sauce

  • 16 oz (450g) penne pasta
  • 15 oz (425g) jar Alfredo sauce
  • ¼ cup milk

Cheeses

  • 1½ cups shredded mozzarella cheese, divided
  • 1 cup shredded cheddar cheese

Seasoning and Garnish

  • Salt and freshly ground black pepper, to taste
  • Fresh parsley, chopped (optional, for garnish)


Instructions

  1. Preheat the Oven: Preheat your oven to 350°F (175°C) and lightly grease a 9×13-inch casserole dish to prepare for baking.
  2. Cook the Chicken: Heat a skillet over medium heat and cook the bite-sized chicken pieces until they are no longer pink, about 5-7 minutes. Season with salt and pepper. Add the chopped onion and minced garlic and cook for an additional 2-3 minutes until fragrant. Remove the skillet from heat.
  3. Cook the Pasta: Bring a large pot of salted water to a boil and cook the penne pasta according to the package instructions until al dente. Drain the pasta thoroughly.
  4. Mix the Casserole: In a large bowl, combine the cooked chicken mixture, drained pasta, Alfredo sauce, 1 cup of shredded mozzarella cheese, and the milk. Stir everything together until evenly mixed.
  5. Assemble & Bake: Spread the combined mixture evenly into the prepared casserole dish. Sprinkle the remaining ½ cup mozzarella and the cheddar cheese evenly over the top.
  6. Bake: Place the casserole dish in the preheated oven and bake for 25 minutes, or until the cheese is melted, bubbly, and slightly golden brown on top.
  7. Serve: Remove from the oven and let the casserole cool slightly before serving. Garnish with freshly chopped parsley if desired for a fresh finish.

Notes

  • You can substitute penne with other pasta shapes like rigatoni or rotini if preferred.
  • For extra flavor, sprinkle some crushed red pepper flakes before baking.
  • Use low-fat milk and cheese for a lighter version of this dish.
  • Leftovers store well in the refrigerator for up to 3 days and can be reheated in the oven or microwave.